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Laser Diffraction

Malvern technology is best in class for implementing laser diffraction on your cannabis powder. This is required for making microparticles based on a quality by design (QbD) principle. The particle size of cannabis powder is an important factor in defining structural, sensory, and functional characteristics. Measurements using the Mastersizer 3000 is used to understand the changes in particle size that occur during production and storage of cannabis powder. This in turn can lead to a better understanding of how product formulation and performance are linked.

A dry system comprises of the main optical unit plus the Aero S dispersion unit. The Aero S is designed for providing an even circulation of dry cannabis powder throughout Mastersizer measurement cell. The microparticles are then pulled through the Mastersizer 3000’s measurement cell using a vacuum. A laser beam passes through the cannabis powder and the angular variation in intensity of the scattered light is measured. Large cannabis particles scatter light at small angles relative to the laser beam and small cannabis particles scatter light at large angles. The spacing and intensity of the rings in the diffraction pattern is related back to the particle size distribution by use of optical models defined by Mie theory, the cannabis industry standard, or Fraunhofer approximation.

  • Observe, control and optimize measurement conditions in real time
  • Rapid, reliable particle size measurements made easy
  • Easy access for cleaning
  • Verifiable accuracy and repeatability