Become a
Have you ever wanted to make drinks without alcohol and want to use THC instead?
Shake, stir, or blend water-soluble THC in your favorite drink and enjoy a divine experience. This food science innovation utilizes proprietary nanotechnology to produce a high-grade emulsion, dispersing nano-sized oil droplets in water called a nanoemulsion. We set the gold standard for food and beverage formulations infused with cannabinoids like delta-9 THC (D9). Our world-class R&D lab has pioneered cannabis beverages, cannabis powder, fast-acting THC, and much more. We believe the world would be a better place if you consumed more cannabis and less alcohol. Enjoy the best THC powder on the planet, exclusively at Le Herbe.
Type
D9 + Limonene
- D9 + Limonene
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
D9 + Caffeine
- D9 + Caffeine
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
D9 + Piperine
- D9 + Piperine
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
D9 + D3K2
- D9 + D3K2
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
D9 + THCv
- D9 + THCv
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
D9 + CBD
- D9 + CBD
- Oral Consumption
- Powder, free-flowing
- Microparticle
- 50–100 μm
- Nanoemulsion
- < 100 nm
- < 0.1
- < -30 mV
- 5–15 min
- 1–2 hrs
- Flavorless
- Odorless
- Terpenes, Flavor, Color
Bioavailability
Figure 1 illustrates the bioavailability of the most common THC products. Many cannabis cultivators and processors focus heavily on plant cultivation, oil extraction, and consumer packaged goods (CPG), yet they often neglect vital research into how edibles are absorbed in the body. Oil-soluble formulations are inefficient, offering consumers an unpredictable experience due to poor bioavailability and solubility, with rapid elimination from the body.
the People
Figure 1
Comparison of cannabis bioavailability (%) for oil-soluble formulations (tincture, gummy, chocolate) vs. inhalation (vape) vs. water-soluble formulations (Le Herbe) vs. intravenous administration (IV). Le Herbe makes THC products that have a higher bioavailability than oil-soluble formulations and inhalation.
Disclaimer: IV is shown for educational purposes only; please don't use this delivery system or think we advocate for it.
Onset Effect
The slow-onset effect of edibles has been a major obstacle to the mainstream acceptance of THC worldwide. As illustrated in Figure 2, oil-soluble formulations can take 1–2 hours for the initial effect after oral consumption and can last up to 4–6 hours. However, in 2015, Le Herbe revolutionized the industry with the introduction of a nanoemulsion and water-soluble THC. This scientific breakthrough allows consumers to feel the effects of THC within 5–15 minutes and dissipate within 1–2 hours. Cannabis brands must prioritize drug absorption with this remarkable discovery or risk being left behind. The game has changed and history is watching.
vs
Long-Lasting
Figure 2
Comparison of THC effects via oral consumption: water-soluble (fast-acting) vs. oil-soluble (long-lasting). Oil-soluble formulations can take 1–2 hours for the initial effect and last up to 4–6 hours. Le Herbe’s water-soluble formulation offers rapid-onset effects within 5–15 minutes and begins to dissipate within 1–2 hours, similar to alcohol’s effects.
FAQs
Beginner
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What are cannabinoids
Le Herbe has a rare collection of high-purity cannabinoids extracted from sun-grown cannabis. The most well-known is delta-9 THC (D9), but this beautiful plant has more than 150 cannabinoids. Each cannabinoid has a specific effect in isolation or in combination with other cannabinoids, terpenoids, and flavonoids (i.e., symphony effect).
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What is the difference between cannabis and hemp
In the USA, cannabis is defined as having greater than 0.3% delta-9 THC, and hemp is defined as having less than 0.3% delta-9 THC on a dry weight basis. Both terms refer to the same plant species, Cannabis sativa L., but the main difference is the concentration of chemical constituents.
The term "hemp" means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.
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How do you grow your cannabis
Le Herbe blends high-quality plant genetics, biodynamic farming, and sun-grown cannabis in our THC powder.
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What type of extract do you use in your THC powder
Le Herbe has proprietary cannabis extracts that may contain a range of cannabinoids, terpenoids, and flavonoids. We prefer to use live rosin or live resin, but the product or desired effect will dictate the appropriate extract to use.
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How should I consume your THC powder
Based on our bioavailability research (AUC), Le Herbe recommends consuming our THC powder in your favorite drink before or while eating a healthy Mediterranean diet (olive oil, fresh fish, nuts, etc.). Intermittent fasting may be a viable alternative.
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How much THC should I consume
Le Herbe recommends 2–10 mg of THC per drink and not more than two drinks per hour. Go low and slow to build up your tolerance, and have fun finding the right amount for personalized enjoyment. Please remember that water-soluble THC is stronger than oil-soluble THC, so you may need to adjust your dosing.
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How long does it take for THC powder to dissolve in water
Complete dispersion or dissolution of Le Herbe's water-soluble powder will be accomplished within a few seconds in warm liquid and in about 30–60 seconds in cold liquid.
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What is a simplified way of explaining a nanoemulsion
A nanoemulsion is like a car. Le Herbe can design a small or large car; we can add more power to the engine; we can speed up or slow down the car; we can change the color of the car; we can put various items in the car and ultimately drive the car to the bloodstream. Simply put, it’s the most versatile delivery system the world has ever seen.
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What is the onset effect of water-soluble THC
Le Herbe's THC powder has an onset effect of approximately 5–15 minutes (fast-acting). Results may vary if you're feasting or fasting, metabolism, gut microbiome, genetics, etc.
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What is the offset effect of water-soluble THC
Oral consumption of Le Herbe's THC powder will have an offset effect of approximately 1–2 hrs. The peak effect is around 45 minutes, and it slowly dissipates.
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What is the onset / offset effect of oil-soluble formulations
The majority of current edible products, like gummies, tinctures, and chocolate, use oil-soluble formulations. They have an unpredictable onset effect (1–2 hrs) and a variable offset effect (4–6 hrs). In addition, you do not absorb the amount of cannabis stated on your product label.
Intermediate
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How do you make cannabis water-soluble
Le Herbe makes a cannabis emulsion that is dispersible in water, and then the water is removed by spray drying or spray chilling to form a water-soluble powder. You can learn more about how we make cannabis water-soluble by reading our legendary white papers.
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Can you include terpenes in a nanoemulsion
Yes. Le Herbe can design a nanoemulsion with terpenes for effect-based formulations. Terpenes can be included in the nanoemulsion itself and/or added to the flavor environment. The flavor of your cannabis beverage has no bearing on the effects of a terpene-based nanoemulsion with THC. Terpenes are less effective when added to the flavor environment than when included directly into the delivery system (nanoemulsion).
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How do you formulate THC into different colors
Le Herbe's team of acclaimed food scientists uses organic fruit and vegetable juice in our THC powders. The specific compounds include anthocyanin, lycopene, and carotenoids. The current color portfolio contains blues, reds, yellows, oranges, and purples. They are flavorless and odorless.
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What type of packaging do you recommend for cannabis drinks
Packaging Description Liquid Powder Bulk Stick Pack metallized film for single-serving ✓ Sachet metallized film for single-serving ✓ Bag metallized film for multiple-servings ✓ ✓ Blister Pack metallized film and/or plastic container for dissolvable tablets ✓ Pod metallized film on a plastic pod for single-serving ✓ Filter + paper filter in a sachet that has metallized film for hot tea ✓ Jar plastic container that is translucent or opaque ✓ ✓ Keg stainless steel vessel for dispensing in a taproom (on tap) ✓ ✓ Bag-in-Box plastic bag in a box for frozen, carbonated or still drinks ✓ ✓ Bottle glass or plastic container that is transparent, translucent or opaque ✓ Can aluminum container with polymer lining on can and lid ✓ -
What is bioavailability
Bioavailability is defined as the percentage of an active ingredient that is able to enter circulation intact after it has been administered. The four main modes of drug delivery are intravenous, inhalation, transdermal, and oral.
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What is the bioavailability of oil-soluble edibles
If you buy a 10 mg cannabis edible that is oil-soluble, then you'll only be consuming about 1.5 mg of the active ingredient (D9). The other 8.5 mg is excreted from your body before you can absorb it. You just paid for 10 mg, but you only absorbed 1.5 mg.
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How do you obtain a bioavailability rating
Cannabis manufacturers will have to develop an in vitro gastrointestinal model in order to obtain bioavailability potential (%) for a specific formulation, food matrix, or consumer packaged good (CPG). You can also hire Le Herbe, and we can do it for you.
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What is the strength of water-soluble THC
Bioavailability will be the new alcohol proof, or ABV, for the cannabis industry, which suggests the true strength of cannabis through quantitative data. This will also be a telltale sign to consumers that your products are professionally formulated using scientific methods and not based on pseudoscience.
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What is the difference between a nanoemulsion and microparticle
A nanoemulsion is a delivery system in a liquid format. A microparticle is a powder that encapsulates a nanoemulsion to protect compounds like D9 from degradation, including but not limited to light, oxygen, heat, and humidity.
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What compound(s) can you combine with THC
Qualified clients can custom order THC powder with one or more of the following compounds.
- 5-HTP
- Caffeine
- Curcumin
- Gingerol
- Kratom
- L-Arginine
- Peptides
- Piperine
- Resveratrol
- Much more...
Advanced
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What is nano
The term “nano” refers to the scale of the particle it describes or the process that makes it. For example, Le Herbe uses a proprietary emulsification process to make an emulsion with delta-9 THC. We measure these particles in nanometers (nm), and the size ranges from 20–100 nm. It can be concluded that Le Herbe uses a nanoemulsification process that makes a nanoemulsion particle. Some companies may use "nano" for marketing cannabis products, but this term is being abused by marketeers and is misleading consumers. Reputable companies provide additional detail with processes and/or actual data to support their claim.
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How do you measure a nanoemulsion
Le Herbe measures a nanoemulsion (liquid) with multi-angle dynamic light scattering (MADLS). This instrument uses MIE theory and includes back (173°), side (90°) and front (13°) scattering data for an accurate measurement. These measurements can refer to particle size distribution (D10, D50, D90), average weighted by surface area (D[3,2]), or average weighted by volume (D[4,3]).
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What is micro
The term “micro” refers to the scale of the particle it describes. For example, Le Herbe uses spray drying or spray chilling to make powder with delta-9 THC. We measure these particles in micrometers (µm), sometimes called microns, and the size ranges from 2–100 µm. It can be concluded that Le Herbe uses a conversion process that makes a complex microparticle. Even though we convert a nanoemulsion into powder, we would not call it a nanoparticle due to the measurement of the exterior structure. The scientific term for this type of particle is an amorphous solid dispersion (ASD). It's important to note an exception to the "micro" nomenclature, and this involves a microemulsion.
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How do you measure a microparticle
Le Herbe measures a microparticle (powder) with laser diffraction and scanning electron microscopy (SEM). These measurements can refer to particle size distribution (X10, X50, X90) or thickness of a particle shell.
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Why is particle size important for cannabis formulations
Overview Description Critical Sinkability the ability of particles to sink below the water surface ✓ Dispersibility the ability of particles to disperse into water ✓ Solubility the ability of particles to disappear and release soluble components ✓ Stability the ability of particles to positively or negatively influence physical and/or physicochemical ✓ Bioavailability the ability of particles to positively or negatively influence absorption ✓ Compressibility the ability of particles to decrease in volume under pressure ✓ Compactibility the ability of particles to compress into a tablet ✓ Mouthfeel the ability of particles to positively or negatively influence texture perception ✓ Taste the ability of particles to positively or negatively influence flavor perception ✓ Smell the ability of particles to positively or negatively influence odor perception ✓ -
Can you grade a nanoemulsion for quality
Yes. Le Herbe developed the world's first grading system for a nanoemulsion
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What does the structure of a nanoemulsion look like
Exterior
Interior
* See additional variations of a nanoemulsion
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What does the structure of a microparticle look like
Exterior
Interior
* See additional variations of a microparticle
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Do you have a video of your powder performance